Integrin Alpha-Beta3 Receptor (Vitronectin Receptor) as a Drug Target and Biomarker

Target Name: Integrin alphavbeta3 (vitronectin) receptor

NCBI ID: P5755

Other Name(s): Vitronectin receptor | alphavbeta3 Receptor | Integrin alphavbeta3

Integrin Alpha-Beta3 Receptor (Vitronectin Receptor) as a Drug Target and Biomarker

Introduction

The Integrin Alpha-Beta3 receptor (Vitronectin Receptor), also known as CD73, is a transmembrane protein that plays a crucial role in cell-cell adhesion, migration, and invasion. It is a member of the integrin family, which is known for its role in cell-cell adhesion and migration, including the regulation of cell growth, differentiation, and survival. The Alpha-Beta3 receptor is expressed in various tissues and cell types, including epithelial cells, endothelial cells, pericytes, and immune cells.

The Alpha-Beta3 receptor is involved in many physiological processes, including cell migration, cell adhesion, and tissue repair and regeneration. It is a potential drug target and biomarker due to its unique mechanism of action and its involvement in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Drug Targeting

The Alpha-Beta3 receptor is a potential drug target due to its unique mechanism of action and its involvement in various diseases. One of the main reasons for its potential as a drug target is its role in cell-cell adhesion and migration. The receptor is known to regulate the formation and maintenance of tight junctions, which are a type of cell-cell adhesion that is critical for various physiological processes, including embryonic development, tissue repair and regeneration, and cancer progression.

In addition to its role in cell-cell adhesion, the Alpha-Beta3 receptor is also involved in the regulation of cell migration and invasion. Alpha-Beta3 receptor has been shown to play a role in the regulation of cell migration and the ability of cancer. cells to invade surrounding tissues.

Biomarker

The Alpha-Beta3 receptor is also a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. One of the main reasons for its potential as a biomarker is its expression in various tissues and cell types, including cancer cells, neurodegenerative diseases, and autoimmune disorders.

In addition to its potential as a drug target and biomarker, the Alpha-Beta3 receptor is also an attractive target due to its unique mechanism of action and its involvement in various physiological processes.

Conclusion

The Alpha-Beta3 receptor is a transmembrane protein that plays a crucial role in cell-cell adhesion, migration, and invasion. It is a potential drug target and biomarker due to its unique mechanism of action and its involvement in various diseases. Further research is needed to fully understand the Alpha-Beta3 receptor and its potential as a drug target and biomarker.

Protein Name: Integrin Alphavbeta3 (vitronectin) Receptor

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